Today we are used to clear divisions between science and the arts. But early modern thinkers had no such distinctions, with 'knowledge' being a truly interdisciplinary pursuit. Each chapter of this collection presents a case study from a different area of knowledge, including the acceptance of heliocentrism and the use of scripture to refute Descartes's claims in A Discourse on Method (1637). The book comes out of an ongoing project, Scientiae, examining the nexus of Renaissance Europe and the history and philosophy of science.