The transport of radioactive material is an essential activity worldwide. To ensure the protection and safety of people, property and the environment, appropriate regulations for the safe transport of radioactive material, both at the national level and at the international level, are necessary. Competent authorities regulate the transport of radioactive material through the application of national regulations, which should be consistent with relevant international regulations. This Safety Guide provides recommendations on actions that competent authorities should take to ensure compliance with the applicable regulations for the safe transport of radioactive material.