fatigue occurs not simply because muscles get tired, but because the brain tells them they’re tired (even though they almost certainly have some reserve fuel and strength remaining), then you can teach your brain to hold off a bit longer, if you should so desire. “I think the training effect of the theory that fatigue occurs in the mind as well as in the muscles is potentially very profound,” Dr. Tucker says. In that case, training “is no longer simply an act of getting the muscles used