Nuclear energy and renewables are the two principal options for low carbon energy generation. However, synergies among these resources have yet to be fully exploited, and the advantages of directly integrating these generation options are being explored. Nuclear-renewable hybrid energy systems consider opportunities to couple these energy generation sources to leverage the benefits of each technology to provide reliable, sustainable electricity to the grid and to provide low carbon energy to other energy use sectors. This publication describes the potential use of nuclear and renewable generation in coordinated, and in some cases tightly coupled, configurations to support various applications beyond electricity production, including desalination, hydrogen production and district heating. Where available, case studies are presented to describe relevant market conditions and trends, and considerations for implementation are outlined, including gaps that require additional technology and regulatory developments.