In this episode of the podcast, Sam Harris speaks with James Fadiman about the psychedelic experience. They discuss who should and shouldn’t take psychedelics, set and setting, the role of a guide, the effects of microdosing, the difference between MDMA and true psychedelics, “good” and “bad” trips, the power of thought, the fiction of a unified self, changing states of self, compassion, and other topics.

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Making Sense with Sam Harris